Researchers develop technology for real-time monitoring of Parkinson's treatments

Sungkyunkwan University researchers have developed a biochip technology that enables real-time monitoring of Parkinson’s disease treatment responses. The university said Tuesday that the “organoid-on-a-chip” technology combines stem cell-derived “mini-brains” with a nanoplasmonic sensor that maximizes light-matter interactions, enabling real-time monitoring of treatment responses. The findings were published in ACS Nano, a leading international journal in nanoscience. The study was conducted by two research teams at the university, each led by Kim In-ki and Park Jong-chan, professors in the Department of Biophysics. The teams included Ph.D. candidates Cho Han-jun and Kim Young-jun and master’s candidate Yoon Na-hyun, who were both first authors of the paper. “This study is significant in that it opens a path to continuously monitoring drug responses in living human tissue over time using an ultra-precision optical sensor,” professor Kim said. “We will further develop the technology into a key platform for patient-specific drug development and disease treatment,” he adde